Tranexamic –Your Skincare Super Ingredient

Tranexamic –”Your Skincare Super Ingredient”

 Achieving flawless, radiant skin is a goal for many individuals around the world. There are numerous factors that can affect the appearance of the skin, including pigmentation disorders such as melasma, hyperpigmentation, and post-inflammatory hyperpigmentation. Fortunately, advancements in skincare have led to the discovery of various treatments, one of which is the remarkable depigmentating power of tranexamic acid.

Understanding Tranexamic Acid:

Tranexamic acid, often referred to as TXA, is an amino acid derivative primarily used for its antifibrinolytic properties, meaning it helps to prevent the breakdown of blood clots. However, recent studies have indicated that TXA can also be an effective treatment for skin pigmentation disorders. When applied topically or taken orally, tranexamic acid acts by inhibiting the production of melanin, the pigment responsible for coloration in the skin, thus minimizing the appearance of hyperpigmentation.

The Depigmentating Action of Tranexamic Acid:

One of the notable benefits of tranexamic acid is its ability to target and improve various forms of pigmentation issues, including melasma, a common skin condition characterized by grayish-brown patches on the face. Research has shown that topical application of TXA can significantly reduce pigmentation in melasma patients, leading to more even-toned skin. Studies have also demonstrated its effectiveness in treating post-inflammatory hyperpigmentation caused by acne scars, hormonal imbalances, or excessive sun exposure.

Mechanism of Action:

The depigmentating action of tranexamic acid is attributed to its ability to inhibit the production of plasmin, an enzyme responsible for breaking down blood clots and activating the inflammatory response. Plasmin can also stimulate the production of growth factors that enhance melanin synthesis. By blocking plasmin and its subsequent effects, tranexamic acid interrupts the melanin production process, resulting in a decrease in pigmentation over time.

Combating UV-Induced Hyperpigmentation:

Exposure to ultraviolet (UV) radiation is a significant contributor to skin discoloration and hyperpigmentation. Tranexamic acid has been found to provide excellent defense against UV-induced pigmentation by reducing the transfer of melanin from melanocytes (pigment-producing cells) to keratinocytes (the outermost layer of skin cells). This unique mechanism helps to prevent the formation of sunspots and freckles, enabling individuals to maintain a more even complexion.

Safe and Suitable for All Skin Types:

One of the advantages of using tranexamic acid is its relative safety and versatility. It is generally well-tolerated by different skin types, including sensitive skin.

At Durban laser clinic we offer a combination of depigmentation treatments and homecare products with tranexamic acid.

The Melan tran3x home depigmenting program incorporates a gel-cream and a concentrate. While the gel-cream attenuates the pigmentation and prevents the appearance of skin spots, the intensive concentrate progressively eliminates the melanin, acting on the darker spots.

The mesopeel® melanostop tran3x is the professional peeling treatment that corrects deep or moderate hyperpigmentation.

Especially developed to treat skin spots, this peeling treatment accelerates the skin’s peeling, rebalances the activity of melanocytes, and inhibits tyrosinase and the inflammatory and vascular components of hyperpigmentation.


The treatment consists of 5 sessions spread out over 15 days for optimal results. 210 depigmentation solution is the transepidermal depigmentation solution that eliminates melanin deposits in the epidermis, regulates the formation of skin spots and inhibits the inflammatory and vascular components of hyperpigmentation.

Its application by microneedling provides optimal efficacy, as in addition to the solutions’ properties, the manual stimulation of the needle promotes collagen synthesis.


In the quest for flawless skin, tranexamic acid has emerged as a promising depigmentating agent, offering a non-invasive solution for various pigmentation concerns. Its ability to target melasma, hyperpigmentation, and post-inflammatory pigmentation makes it a sought-after ingredient in the realm of skincare. However, for optimal results, it is crucial to establish a comprehensive skincare routine. Embrace the depigmentating power of tranexamic acid, and unlock the potential for a more even, radiant complexion.

Contact Us

"*" indicates required fields

Would you like to receive subscriber only discounts and promotions?*

Coffee creative logo2018 Brew by Coffee Creative Studio